Arboviruses

            Arboviruses are arthropod-borne viruses, viruses of vertebrates biologically transmitted by blood-sucking insects. They multiply in them, transmitted by bite to vertebrate hosts. Arboviruses  have a very wide host range including many species of animals and birds. The ability to multiply in arthropods is their special characteristic. The most important arbovirus vectors are mosquitoes and ticks. In the laboratory, mice are commonly used for growing arboviruses. They can be grown in the yolk sac or chorioallantoic membrane of chick embryo, in tissue cultures of primary cells like chick embryo fibroblasts, HeLa cells. Most arboviruses agglutinate the red cells of one-day old chicks. Hemagglutination is influenced by pH , temperature etc. Arboviruses are labile, inactivated at room temperature, bile salts, ether.